<?xml version="1.0" encoding="UTF-8"?><rss xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:content="http://purl.org/rss/1.0/modules/content/" xmlns:atom="http://www.w3.org/2005/Atom" version="2.0" xmlns:itunes="http://www.itunes.com/dtds/podcast-1.0.dtd" xmlns:googleplay="http://www.google.com/schemas/play-podcasts/1.0"><channel><title><![CDATA[Quintessential Medicine]]></title><description><![CDATA[The Medical Profession has gone off the rails. Science and ethics are gone. I am a classically trained clinician, board certified in Internal Medicine and Nephrology. Follow this substack to learn about how we get back on track. ]]></description><link>https://richardamerlingmd437332.substack.com</link><image><url>https://substackcdn.com/image/fetch/$s_!QnPm!,w_256,c_limit,f_auto,q_auto:good,fl_progressive:steep/https%3A%2F%2Frichardamerlingmd437332.substack.com%2Fimg%2Fsubstack.png</url><title>Quintessential Medicine</title><link>https://richardamerlingmd437332.substack.com</link></image><generator>Substack</generator><lastBuildDate>Sat, 30 May 2026 18:12:39 GMT</lastBuildDate><atom:link href="https://richardamerlingmd437332.substack.com/feed" rel="self" type="application/rss+xml"/><copyright><![CDATA[Richard Amerling, MD]]></copyright><language><![CDATA[en]]></language><webMaster><![CDATA[richardamerlingmd437332@substack.com]]></webMaster><itunes:owner><itunes:email><![CDATA[richardamerlingmd437332@substack.com]]></itunes:email><itunes:name><![CDATA[Richard Amerling, MD]]></itunes:name></itunes:owner><itunes:author><![CDATA[Richard Amerling, MD]]></itunes:author><googleplay:owner><![CDATA[richardamerlingmd437332@substack.com]]></googleplay:owner><googleplay:email><![CDATA[richardamerlingmd437332@substack.com]]></googleplay:email><googleplay:author><![CDATA[Richard Amerling, MD]]></googleplay:author><itunes:block><![CDATA[Yes]]></itunes:block><item><title><![CDATA[What is "Quality Healthcare?"]]></title><description><![CDATA[Hint: It's not about metrics]]></description><link>https://richardamerlingmd437332.substack.com/p/what-is-quality-healthcare</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/what-is-quality-healthcare</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Tue, 17 Mar 2026 13:50:09 GMT</pubDate><enclosure url="https://substackcdn.com/image/youtube/w_728,c_limit/xZFjPbU6Ql0" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>Here&#8217;s a recent podcast about my old essay, &#8220;Zen and the Art of Health Maintenance.&#8221;</p><p></p><div id="youtube2-xZFjPbU6Ql0" class="youtube-wrap" data-attrs="{&quot;videoId&quot;:&quot;xZFjPbU6Ql0&quot;,&quot;startTime&quot;:null,&quot;endTime&quot;:null}" data-component-name="Youtube2ToDOM"><div class="youtube-inner"><iframe src="https://www.youtube-nocookie.com/embed/xZFjPbU6Ql0?rel=0&amp;autoplay=0&amp;showinfo=0&amp;enablejsapi=0" frameborder="0" loading="lazy" gesture="media" allow="autoplay; fullscreen" allowautoplay="true" allowfullscreen="true" width="728" height="409"></iframe></div></div><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Quintessential Medicine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[The Destruction of American Medicine and Health: An Eyewitness Account]]></title><description><![CDATA[How Medicine Lost Its Way, and How To Get Back On Track]]></description><link>https://richardamerlingmd437332.substack.com/p/the-destruction-of-american-medicine</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/the-destruction-of-american-medicine</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Mon, 02 Feb 2026 17:26:07 GMT</pubDate><content:encoded><![CDATA[<p><strong>The Destruction of American Medicine and Health: An Eyewitness Account</strong></p><p>Adapted from a presentation to Medical Doctors for Covid Ethics, January 20, 2026</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Quintessential Medicine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p><strong>Intro:</strong></p><p>I&#8217;ve had a very strong scientific education, beginning with Stuyvesant High Schooo, then Physics and Chemistry in college and medical school in Belgium at the Catholic University of Louvain, known for its heavy emphasis on Basic Science and Medical Ethics.</p><p>While in medical school, I came to completely reject the theory of evolution based on the scientific implausibility of the spontaneous appearance of living creatures with increasingly complex features, and the irreducible complexity of life at the molecular level.</p><p>I also read Karl Popper and adopted his definition of scientific, as opposed to pseudoscientific, theories, as those capable of being disproven by experimentation. If there&#8217;s no possible experiment or observation that would be able to disprove a hypothesis, it is not truly scientific. Other examples of pseudoscience include Marxism, psychoanalysis, and of course &#8220;climate change.&#8221;</p><p>As a corollary to this foundational principle, a true scientific hypothesis is never &#8220;proven;&#8221; it can only be disproven. The classic example: The hypothesis that &#8220;all swans are white&#8221; is completely disproven by the demonstration of a single black swan. Experiments can support but not prove a hypothesis.</p><p>Another major influence during my college years was the classic book by Robert Pirsig: &#8220;Zen and the Art of Motorcycle Maintenance.&#8221; This led me to pen an essay some years ago critiquing Health Maintenance Organizations (HMO) entitled &#8220;<a href="https://richardamerlingmd437332.substack.com/p/whither-quality">Zen and the Art of Health Maintenance.</a>&#8221; I put forward the notion that quality in medical care depended entirely on the quality of the patient-physician interaction.</p><p>And the brilliant Buckminster Fuller&#8217;s &#8220;Operating Manual for Spaceship Earth&#8221; completely debunked the Malthusian nutcase Paul Ehrlich&#8217;s &#8220;The Population Bomb.&#8221;</p><p><strong>Destruction of Medicine:</strong></p><p>I was an eyewitness to the destruction of the medical profession and have pushed back for my entire career, mostly through the Association of American Physicians and Surgeons (aapsonline.org) where I served as president in 2015 and board member for many years.</p><p>After residency in Internal Medicine in New York, and a Nephrology fellowship at the Hospital of the University of Pennsylvania in the &#8216;80s, I began my career as an academic nephrologist at New York&#8217;s Beth Israel Medical Center, a teaching hospital initially of the Mount Sinai School of Medicine. It&#8217;s painful to recall how wonderful it was being a doctor back then, compared with the current state of affairs.</p><p>Doctors were a highly selected group of intelligent, fiercely independent overachievers; 90% were in private practices they owned. Private medical care in America was the envy of the world.</p><p>Most patients in hospital were admitted and followed by their private doctors. To get hospital privileges, private docs had to do at least a month of service, i.e., teaching rounds; most were excellent.</p><p>The private medical staff was a powerful group in the hospital. Many hospitals were run by physicians. The Doctors&#8217; Lounge was off limits to patients, visitors, and administrators. I wonder if any still exist today.</p><p>Over the years, private doctors were completely pushed out by administration, their roles taken over by &#8220;hospitalist&#8221; physicians fully employed by the hospital; their primary job was to assure the rapid discharge of patients, as this maximized revenue under Medicare&#8217;s &#8220;diagnosis related group&#8221; payment scheme.</p><p>Pharma was present but on the periphery. They had their &#8220;key opinion leaders&#8221; pushing products and reps courted doctors, certainly, but we remained true to our patients. Doctors assessed new drugs with appropriate skepticism.</p><p>Journals were excellent, especially the Lancet and the NEJM, both of which I read regularly. The Lancet was printed on thin paper, black and white, without ads and was full of clinically useful and timely reports. Turnover time for acceptance or rejection of articles submitted for publication was one week!</p><p>Our bibles were Harrison&#8217;s Principles of Internal Medicine, and Cecil. Patient problems provided the impetus to research, and we frequently went to the hospital library to pull articles. We carried the Washington Manual and photocopied articles on rounds for quick reference. We wrote progress notes in paper charts by hand.</p><p>There were three major elements that led to the demise of the medical profession: Loss of financial independence, loss of professional autonomy, and abandonment of medical ethics.</p><p><strong>Financial Independence</strong></p><p>Physicians surrendered their financial independence by gradually accepting third-party payment for their services. As we will discuss later, third-party payment (the veterinary model) is inherently unethical as it intrudes on medical decision-making and the patient-physician relationship. The major force driving this change was Medicare. It was initially sold as no-strings-attached insurance program for the elderly that would reimburse for doctors&#8217; usual, customary, and reasonable charges with no questions asked. As program costs exploded to over 10x predicted, a series of controls were instituted. Eventually participation in Medicare required physicians to accept their reimbursement as payment in full; in other words, &#8220;balance billing&#8221; was ended. Private insurers followed suit. While their payments typically exceeded those set by Medicare, doctors were contractually bound to accept them as full payment. Once doctors surrendered the ability to set their own rates (lawyers, dentists, accountants) their fate was sealed.</p><p>Physicians in private practice in essence became employees of the insurance provider and gave up considerable control over the way they practiced medicine. They also became completely dependent on the whims of reimbursement policy.</p><p>Payment for doctors&#8217; services were set using the RBRVS, a Stalinist concoction that attempted to quantify physicians&#8217; work product. Payments progressively declined in both the public and private sectors, leading to increasing volume of services, less time per patient, and declining quality of care. The cost of running an office went through the roof since additional staff were required for billing, coding, collection, and maintaining an EHR.</p><p>The &#8217;80s and &#8216;90s saw the rise of Managed Care and the HMO. This was a scam, where patients were assigned a Primary Care Provider (PCP, provider) who was contracted to serve as a &#8220;gatekeeper,&#8221; in other words, to ration care. These plans became dominant; open-ended indemnity plans suddenly were very expensive and hard to find.</p><p>Since third party payment drove up the cost of care dramatically, few could afford to go without insurance, and denial of payment for various tests or procedures effectively made those options unavailable (MRI, etc). Doctors suddenly had to spend precious time getting &#8220;pre-authorizations&#8221; for virtually everything more costly than aspirin!</p><p>Financial incentives were introduced to control medical practice through various &#8220;payment for performance&#8221; schemes (P4P). Performance metrics continue today and usually consist of following industry guidelines.</p><p>The highly partisan passage of Obamacare dramatically increased regulations and restraints on practice, and we saw &#8220;high deductible, high premium&#8221; plans offered to individuals and a huge expansion of the Medicaid program.</p><p>These heavy expenses, increasing workload, along with lower income, led to a massive migration out of private practice and into large group practices, mostly owned and run by hospital corporations. Doctors went from being <em>de facto</em> employees to being <em>in facto</em> employees and completely lost their financial independence.</p><p>According to a 2022 article in Becker&#8217;s:</p><p>The number of physicians in private practice <a href="https://www.beckersasc.com/asc-transactions-and-valuation-issues/private-practice-physicians-drop-to-26.html">dropped</a> to 26 percent in 2021.</p><p>There are now about 135,300 hospital or corporate-owned physician practices in the U.S.</p><p>About 108,700 physicians have left private practice since January 2019</p><p><strong>Loss of Autonomy</strong></p><p>The loss of professional autonomy means losing the ability to make independent clinical assessments and treatments based on scientific principles, training, clinical experience and judgment. The Hippocratic Oath states, &#8220;I will prescribe regimen based on my judgment and training (consulting colleagues as needed.&#8221;</p><p>This began to fall away during the &#8216;90s with the widespread acceptance by the profession of the pseudoscientific cult of &#8220;evidence-based&#8221; medicine (EBM). This Canadian construct arrogantly claimed the moral and scientific high ground by implying that everything before EBM was based on superstition, sorcery, alchemy, and witchcraft.</p><p><strong>Problems with EBM:</strong></p><p>To begin, &#8220;evidence&#8221; is not science, and can be found or manufactured to support any conceivable hypothesis. Flat earthers, climate change zealots, and others cite mountains of &#8220;evidence&#8221; favoring their absurd and implausible notions.</p><p>As stated earlier, scientific hypotheses can be supported by experiments (studies), or disproven, but never proven. Remember this when you hear claims that Drug X has been &#8220;proven effective.&#8221; No! This is a key issue.</p><p>Since &#8220;scientific proof&#8221; doesn&#8217;t exist, EBM substitutes &#8220;legal proof&#8221; based on statistics and the &#8220;preponderance of evidence.&#8221;</p><p>EBM creates an arbitrary hierarchy of &#8220;evidence&#8221; with randomized, controlled trials (RCTs) at the top (later replaced by the metanalysis), and clinical experience at the bottom. This is absurd on its face&#8212;RCTs are easily manipulated and often flawed, while clinical experience is the basis of medical practice. Even a well-designed, unbiased RCT (try to find one) provides at best a statistical probability that a given treatment will be helpful to the patient in your office. Not everyone in the treatment arm does well, and not everyone in the placebo arm does poorly.</p><p>There is never enough granular information in a trial to allow doctors to apply the results broadly to everyone, yet that is exactly what has developed.</p><p>Using principles derived from EBM, Big Pharma cleverly funded expert panels to create &#8220;clinical practice guidelines&#8221; (CPG) for the treatment of now virtually every condition. Not coincidentally, many panelists have significant financial conflicts of interest&#8212;they are paid by industry. Unsurprisingly, most CPGs recommend Pharma treatments, larger doses, and to ever bigger swaths of the population.</p><p>Guidelines now dominate medical school education, leading to rigid, non-critical thinking; &#8220;settled science&#8221; rather than curiosity. In fact, Pharma now controls virtually every level of medical education, leading to what Toby Rogers calls, &#8220;epistemic capture.&#8221;</p><p>I saw guidelines enter Nephrology around 2000 and was immediately suspicious; I began <a href="https://richardamerlingmd437332.substack.com/p/guidelines-have-done-more-harm-than">writing</a> and debating with colleagues, urging them to stop creating and using them. Amgen sponsored guidelines by the National Kidney foundation for treatment of anemia with their blockbuster drug recombinant human erythropoietin (Epogen) that recommended treating to levels of hemoglobin entirely unsupported by existing medical literature, which led to major harms. Most panelists reported being paid by Amgen and other Pharma companies.</p><p>Guidelines typically focus on &#8220;risk factors&#8221; for disease, rather than the actual disease. These are most often numerical &#8220;targets,&#8221; such as blood pressure, LDL-C, T-scores, or glycosylated hemoglobin (HbA1c). These targets move: Ever-increasing drug treatments are justified to get patients &#8220;to goal.&#8221; Disease reversal by treating underlying causes is almost never addressed. This is what most mainstream medical practices have devolved to.</p><p>Outcomes are poor with this approach. Doctors prescribe insulin and other drugs for type 2 diabetes to lower blood glucose and HbA1c when the disease is easily reversible with a low carb/no sugar/high saturated fat diet.</p><p>Practice guidelines have allowed the &#8220;standard of care&#8221; to morph into &#8220;standardized care.&#8221; This is nothing more than &#8220;one-size-fits all;&#8221; the antithesis of good, individualized care. Going outside the &#8220;standard&#8221; places physicians in jeopardy of losing their employment, certification, or even their license to practice. This is the complete triumph of &#8220;Public Health,&#8221; a Marxist creation, over personalized care.</p><p>Granting unjustified authority to various official bodies, such as the CDC or WHO, most of whose members do not even treat patients, has led us to the <a href="https://www.jpands.org/vol26no4/amerling.pdf">medical tyranny</a> we have been experiencing for the last few years. What is &#8220;misinformation and disinformation?&#8221; Anything that runs counter to the official &#8220;guidance,&#8221; or consensus.</p><p><strong>Lapsed Ethics</strong></p><p>Medical Ethics has been either abandoned wholesale or highly manipulated over the last 40+ years. The Oath of Hippocrates remains the gold standard expression of medical ethics. It is a solemn pronouncement by which a physician acknowledges and pledges oneself to the priority of patient well-being, and to confidentiality, precaution, beneficence and non-maleficence over coercion, compliance and self-interest.</p><p>So much of what is currently practiced is unethical. Reaffirmation of Medical Ethics is an absolute precondition to the restoration of the medical profession.</p><p>Medical confidentiality is crucial to the ethical practice of medicine and should be absolute. Sadly, it was surrendered without so much as a whimper way back when the first diagnostic code was entered into a billing form. Third party payers do not have a right to this information, and it should never have been allowed.</p><p>Risk vs. benefit analysis is essential to &#8220;do no harm.&#8221; It is almost never performed. No vaccines even come close to passing this test, and the same is true for the majority of commonly prescribed drugs for &#8220;chronic diseases,&#8221; most of which are caused by poor diet.</p><p>Rarely is true informed consent given to patients, even for commonly prescribed drugs, the majority of which do more harm than good! No one who was pushed into getting jabbed was informed of the risks, and the complete lack of efficacy, for example.</p><p>Speaking of being pushed, coercion in any form makes a mockery of informed consent and is highly unethical. Children and their parents today are being coerced into embarking on a &#8220;gender change&#8221; journey that is inherently harmful, not to mention completely antiscientific. There are only two genders, determined by chromosomes, and changing gender is an impossibility.</p><p>Abortion is the taking of an innocent human life. It is unambiguously proscribed in the Hippocratic Oath.</p><p>The <a href="https://www.jpands.org/vol20no3/amerling.pdfhttps:/www.jpands.org/vol20no3/amerling.pdf">loss of an independent, free-thinking, ethical Medical Profession has been a catastrophe. </a>It&#8217;s not a coincidence that independent practices have been targeted and crushed. They have traditionally been a bulwark against destructive and insane policies, such as eugenics. The eugenics movement originated in liberal and academic circles in the US but got no traction because private physicians were never going to be OK with euthanizing patients for the greater good! This was not the case in Germany. Hitler stole eugenics from us and had co-opted the medical profession in various ways. German doctors had the highest Nazi Party participation of all professions (nurses were not much better) and led the way on euthanizing retarded children, mental patients, the chronically ill, and ultimately the Jews.</p><p>A few years ago I wrote &#8220;<a href="https://aapsonline.org/the-nazification-of-american-medicine/">The Nazification of American Medicine,&#8221;</a> based on the horrible response to Covid-19.</p><p><em>&#8220;Most American doctors followed CDC and Food and Drug Administration (FDA) &#8220;guidance.&#8221; They withheld early life-saving treatments. They abandoned patients, instructing them to stay home until they literally couldn&#8217;t breathe. They did not object to the blatant, harsh censorship and harassment of colleagues who were utilizing repurposed drugs to fight the disease. They failed to recommend general health measures aimed at improving metabolic and immune health.</em></p><p><em>&#8220;Doctors did not object to the imposition of mask mandates, despite clear evidence of their lack of benefit and obvious harms, especially to young children. Nor did they protest lockdowns, whose inefficacy and massive collateral damage were immediately evident.</em></p><p><em>&#8220;Once a patient was in hospital, doctors complied with absurd and inhumane rules restricting family visitation of sick and dying patients and followed strict treatment protocols that were at best ineffective, and at worst lethal. Government payments to hospitals incentivized diagnosing COVID-19 and following the &#8220;guidelines.&#8221;. These included the mandatory prescription of <a href="https://rairfoundation.com/first-degree-murder-remdesivir-is-being-used-to-kill-us/">remdesivir,</a> an ineffective and highly toxic drug, pushed into guidelines by Anthony Fauci. The protocols excluded the use of inhaled steroids, and recommended dexamethasone, a weak systemic corticosteroid, at very low doses. Full anticoagulation was hard to come by in a disease known to cause major blood clotting.</em></p><p><em>&#8220;For the most part, doctors enthusiastically backed the mass &#8220;vaccination&#8221; of all humans, regardless of any clinical considerations such as prior immunity, low risk of severe disease, pregnancy, and many other clear contraindications. They even denied life-saving organ transplantation when either donor or recipient was unvaccinated, a policy with zero scientific merit.</em></p><p><em>&#8220;What about human experimentation? These gene-based &#8220;vaccines&#8221; are all experimental. How many participants have given truly informed consent? How many were told the absolute risk reduction for serious infection is less than 1%?</em></p><p><em>&#8220;There is no way to measure definitively how many have died because of these centrally ordered practices. Possibly millions. One telling indicator <a href="https://thehill.com/changing-america/well-being/longevity/588738-huge-huge-numbers-death-rates-up-40-percent-over-pre/">may be the 40% spike</a> in life insurance claims for working age adults reported in 2021.</em></p><p><em>In other words, the Medical Profession should have stood up en masse and pushed back against these unscientific and unethical policies. We failed miserably.</em></p><p><strong>The Destruction of American Health:</strong></p><p>Four main causes:</p><p>1. Dietary guidelines&#8212;&gt;toxic food environment</p><p>2. Mass vaccination: All harm, no benefit</p><p>3. Pharma-Based Medicine (PBM): Treating numbers and symptoms</p><p>4. Covid-19: Disease and response</p><p>In the interest of time, I will focus here on diet, which I believe is the major issue, and one that is relatively easy to remedy.</p><p><strong>The DGA and the demonization of saturated fat</strong></p><p>The first reported case of myocardial infarction was in 1910 and the first report of coronary thrombosis was in 1912. The incidence steadily increased over the first half century to what became alarming levels during the 1950s, culminating in Dwight D. Eisenhower&#8217;s heart attack in 1955. This provoked a national debate over the cause of the epidemic of coronary artery disease. There were several plausible explanations: A huge increase in smoking, especially after WW2; major increases in sugar consumption; introduction of vegetable seed oils, margarine and shortening (Crisco). Oddly enough it was the least plausible explanation that won the debate&#8212;that saturated fat, which our ancestors thrived on for millennia, was the culprit.</p><p>This bizarre idea was pushed by a bizarre man, Ancel Keys, a self-described physiologist and originator of K-rations. He became convinced, based on observations in a handful of countries, that saturated animal fats, by increasing cholesterol, were the cause of heart disease. He pressed his case aggressively, often with personal attacks on those who disagreed with him, such as British scientist John Yudkin. His fraudulent 7-Countries Study looked at population consumption of saturated fat and incidence of coronary artery disease. He cherry-picked only the countries that fit his hypothesis (<em>7 of 22, omitting France. The French diet, rich in butter, meat, cheese, foie gras, and other sources of saturated fat doesn&#8217;t lead to obesity or coronary artery disease. This observation disproves the diet-heart hypothesis. Rather than abandon it, they call it the French Paradox</em>). It was egregious junk science. He was then hired to provide nutritional guidance by the American Heart Association.</p><p>The AHA was ushered into existence and sustained by multi-million dollar grants from Procter &amp; Gamble, the original makers of Crisco; they continue to push the anti-saturated fat propaganda to this day. Thus, Keys and the AHA were shills for fake fats.</p><p>Keys, the AHA and industry lobbyists pushed through the DGA through the McGovern Commission, which led to the USDA&#8217;s Food Pyramid, stressing minimal consumption of saturated fats, 50% of calories as grains. Nina Teicholz in her excellent book, &#8220;The Big Fat Surprise,&#8221; goes into this topic in great detail.</p><p><strong>What about sugar?</strong></p><p>Table sugar (sucrose, dextrose) is roughly 50% glucose and 50% fructose. Glucose can be utilized for energy by most cells in the body.</p><p>The glucose component of sucrose is metabolized via glycolysis with production of 2 ATP (anaerobic). Glucose stimulates insulin release which blocks fat mobilization. Pyruvate is then metabolized aerobically via the Krebs Cycle with several more ATP produced. Glycolysis consumes oxygen and produces an equal amount of CO2. Glucose provides quick energy and is rapidly depleted. Glucose not used for energy is stored as fat.</p><p>Fructose is metabolized exclusively in the liver and overconsumption leads to excess production of fatty acids which can accumulate and lead to fatty liver disease (now rampant in children!</p><p>The fructose component makes sugar particularly toxic compared with slowly digested carbohydrates, which are broken down to glucose.</p><p>The case against sugar as cause of heart disease was very strong and had considerable scientific backing. Then, in 1967, highly influential review articles were published in the New England Journal of Medicine by three Harvard scientists, Frederick Stare, Mark Hegsted, and Robert McGandy, downplaying sugar&#8217;s role in heart disease, and supporting Keys&#8217; saturated fat hypothesis. In 2016, investigative journalist Cristin Kearns unearthed letters showing these doctors were each paid $6500 ($61,000 today) for their work by the Sugar Association, who also were heavily involved in editing the articles. These payments were not made public at the time. This clever and diabolical strategy paid off, as sugar was given a pass by the public.</p><p>The food industry jumped in with scores of &#8220;low fat&#8221; processed foods, filled with seed oils and sugars.</p><p>The health of the nation began a long decline, led by the obesity epidemic, which began in 1980 and is still raging.</p><p>In the &#8216;50s-&#8216;70s, when I grew up, almost everyone was slim. No one exercised or dieted! Fat people stood out. In 1968, I was one of half a million skinny, longhaired hippies at the Woodstock Festival. Fast forward to the present day: 75% of the population is overweight/obese and most of these have the Metabolic Syndrome. The harm from these guidelines is incalculable!</p><p>If Covid is the Crime of the 21<sup>st</sup> Century, the DGA was the Crime of the 20<sup>th</sup> Century!</p><p><strong>The Metabolic Syndrome (MetS)</strong></p><p>MetS is defined clinically as the constellation of central obesity, type 2 diabetes, abnormal lipids (high TG, low HDL), hypertension, and vascular disease. The pathophysiology involves overconsumption of sugar and processed carbohydrates leading to chronic secretion of insulin and insulin resistance. High levels of insulin are behind most of the complications, such as hypertension. Fatty liver, caused by fructose, is also a major player in MetS.</p><p>Most doctors regard diabetes and hypertension as separate diseases and treat each separately with various drugs. They simply fail to recognize they are both symptoms of an underlying metabolic syndrome that is readily reversible with a proper diet!</p><p>Insulin signals cells to store energy as fat, and to grow. Hyperinsulinemia is the obvious link between obesity and over 70% of cancers.</p><p>Metabolic syndrome is very likely responsible for the epidemic of Alzheimer&#8217;s dementia.</p><p>The key to reversing obesity and the MetS is to lower insulin levels. This is accomplished by cutting out most sugars, reducing carb intake to &lt;100 g/d, eliminating seed oils, and intermittent fasting (no snacks). Read labels and avoid the center aisles of the supermarkets! If people stop buying this toxic garbage, Big Food will stop making it. Most restaurants use seed oils for frying because they are inexpensive. Deep fryers reuse seed oils for a week or more, ensuring high levels of toxic metabolites, such as aldehydes. Request safe oils such as butter, ghee, tallow or coconut oil. Eventually, if enough of us do this, restaurants will change.</p><p><strong>Fat Fysiology:</strong></p><p>Fat is oxidized in the mitochondria with production of 129 ATP for a long chain fatty acid. For each mole of oxygen consumed, only 0.7 mole of CO2 is generated. If you believe CO2 is destroying the planet (and I certainly do not!), you should go keto (this is for humor, since many in that camp are &#8220;plant-based&#8221;). Fat oxidation provides virtually limitless energy and produces ketones, which are the preferred energy substrate for the brain and heart. Nutritional ketosis is, in my view, the default condition for which we were designed.</p><p>Vegetable seed oils contain mostly PUFA which are pro-inflammatory and obesogenic. Oxidation of saturated fatty acids in mitochondria produces intermediaries that block the action of insulin to store energy in adipose tissue. Polyunsaturated fat oxidation lacks this benefit.</p><p>When heated, PUFA become aldehydes that are quite toxic.</p><p>The guideline-driven switch from saturated fat to polyunsaturated seed oils is one of the principal drivers of the obesity/metabolic syndrome epidemic.</p><p><strong>Cholesterol</strong></p><p>The Cholesterol scam has also harmed millions, while generating billions in Pharma profits.</p><p>1. Cholesterol doesn&#8217;t cause heart disease. This hypothesis is disproved by the millions with low or &#8220;normal&#8221; cholesterol who have heart attacks every year, and the millions with &#8220;high&#8221; cholesterol who do not.</p><p>2. Cholesterol is a vital substance synthesized by most cells in the body. It&#8217;s essential to brain and nerve function and plays a key role in the immune system.</p><p>3. Cholesterol is the backbone upon which is built vitamin D, cortisol, aldosterone and the sex hormones.</p><p>4. Blocking the mevalonate pathway (statins) depletes other key compounds such as dolichols and CoEnzyme Q10; vital for energy transport. It&#8217;s inconceivable that blocking this key biosynthetic pathway could be anything but harmful</p><p>5. The cholesterol blocked by statins is the same molecule in HDL (good) and LDL (bad).</p><p>6. Dietary cholesterol has no impact on blood levels.</p><p>7. Studies of cholesterol lowering show no mortality benefit.</p><p>8. Phony &#8220;relative risk reduction&#8221; math is used to sell statins which at most produce 1-3% absolute risk reduction in &#8220;events.&#8221;</p><p>9. As in most Pharma studies, harms are downplayed but are very real and sometimes deadly. Examples: myositis, rhabdomyolysis, brain fog (aka dementia!), diabetes, neuropathies, amyotrophic lateral sclerosis (ALS, Lou Gehrig&#8217;s disease).</p><p><strong>Caloric Nonsense:</strong></p><p>This fiction creates the impression that calories from different foods are equivalent in terms of weight control, and that fat (9 kcal/gm) is more obesogenic than carbs or protein (4 kcal/gm). This is demonstrably absurd. The insulin response to food is what counts: Carbs/sugars trigger insulin release which drives energy storage as fat. Fat doesn&#8217;t provoke insulin or energy storage.</p><p>Constant snacking or multiple small meals as many dieticians recommend will guarantee continuous weight gain. To utilize energy stored as fat, insulin levels must be suppressed. This requires a prolonged fast (12-18 hours) and low carbohydrate intake.</p><p>Carbs are an inefficient source of energy and produce insulin/blood glucose peaks and valleys which drive more carb/sugar intake.</p><p>Weight reduction strategies based on calorie reduction never work! Read &#8220;The Obesity Code&#8221; by Dr. Jason Fung for a deep dive into this topic.</p><p><strong>Salt:</strong></p><p>Salt is essential for life and should be restricted only in those with heart, kidney, or liver failure. Everyone else should liberally use salt to taste. Low salt intake produces a variety of health problems and triggers counter regulatory hormonal systems that create harm.</p><p><strong>Saving the Medical Profession and Restoring Health</strong></p><p>How do we take Medicine back? The current system is too corrupt, too Pharma-controlled to be fixed. We need to create a parallel system. It&#8217;s our calling to preserve Hippocratic Medicine for future generations.</p><p>1. <strong>Reestablish medical ethics and financial independence</strong>. (Join GoldCare and AAPS)</p><blockquote><p>a. Ditch 3<sup>rd</sup> party payment entirely: Direct payment only (essential that patients embrace this concept!)</p><p>b. Leave corporate practice</p><p>c. Restore medical confidentiality</p><p>d. Restore informed consent</p><p>e. Do No Harm: Risk v benefit should guide all decisions.</p><p>f. Restore the patient-physician relationship to its place of primacy</p></blockquote><p>2. <strong>Restore Science:</strong> The concept of &#8220;misinformation and disinformation&#8221; in science and medicine must be rejected at the highest level. No one holds a monopoly on the truth. Protections for doctors to practice independently must be enacted by legislatures around the country.</p><blockquote><p>a. Reject EBM</p><p>b. Abolish practice guidelines</p><p>c. Re-learn the Basic Sciences</p><p>d. Use knowledge of basic science to prevent, reverse, and cure disease</p><p>e. Stop treating &#8220;risk factors.&#8221;</p><p>f. Deprescribe</p><p>g. Focus on healthy eating and lifestyle, especially LCHF (keto) and intermittent fasting.</p></blockquote><p><strong>3. Take back Medical Education</strong></p><blockquote><p>a. Focus on basic and clinical science</p><p>b. No &#8216;wokeism&#8217; allowed (Do No Harm)</p><p>c. No EBM or guidelines</p><p>d. Abolish all Schools of Public Health</p></blockquote><p><strong>Restoring Our Health</strong></p><p><strong>Diet:</strong> Do the opposite of official &#8220;guidance.&#8221; The &#8220;pyramid turned upside down&#8221; as has recently been done under the new HHS secretary.</p><p>1. Eat saturated fats: Butter, cream, meat, (pastured) eggs, bacon (from pastured pigs, if possible)..</p><p>2. Avoid vegetable seed oils like the plague</p><p>3. Cholesterol is your friend; lowering it is harmful. Don&#8217;t take statins.</p><p>4. Grains (carbs) should be consumed sparingly</p><p>5. Sugar is to be avoided.</p><p>6. Don&#8217;t count calories</p><p>7. Intermittent fasting: Do not snack</p><p>8. Muscle strengthening with resistance is highly beneficial</p><p>9. Salt your food!</p><p><strong>Vaccinations:</strong> I personally believe that all vaccines fail risk vs. benefit analysis for individuals and do not improve population health. Mortality risk for all vaccines on the childhood schedule exceeds that for the diseases they supposedly prevent. True placebo-controlled safety trials haven&#8217;t been performed. Moving away from them will be difficult due to the enormous financial interests behind their continued use. At the very least we must eliminate all mandates for vaccines if only because the violate informed voluntary consent and medical ethics. We should also eliminate financial incentives to doctors to administer them. Read &#8220;Vax Facts&#8221; by Dr. Paul Thomas and &#8220;Vaccines, Amen&#8221; by Aaron Siri. And of course, &#8220;Dissolving Illusions&#8221; by Suzanne Humphries and Roman Bystrianyk.</p><p><strong>Pharma-Based Medicine (PBM):</strong> Mainstream practice of medicine has become harmful to health!</p><p>Patients should seek clinicians who reject PBM and who strive to understand and correct underlying problems and reverse diseases rather than treat numbers based on Pharma protocols. For this, I can safely recommend joining us at GoldCare.com; we are resuscitating the patient-physician relationship.</p><p><strong>Covid-19:</strong> Both the disease and its official &#8220;remedies&#8221; have had devastating effects on national and world health. This discussion is beyond the scope of this presentation. Bottom line: Don&#8217;t take any &#8220;boosters&#8221; or &#8220;vaccinations&#8221; against new &#8220;pandemics.&#8221; If you have been jabbed, restoring excellent metabolic health is paramount.</p><blockquote><p></p></blockquote><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Quintessential Medicine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[Guidelines Have Done More Harm Than Good]]></title><description><![CDATA[From a 2008 article published in Blood Purification]]></description><link>https://richardamerlingmd437332.substack.com/p/guidelines-have-done-more-harm-than</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/guidelines-have-done-more-harm-than</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Sat, 03 Jan 2026 02:37:36 GMT</pubDate><content:encoded><![CDATA[<p>Introduction: <em>These excerpts are from an article I wrote in 2008 in response to the proliferation of practice guidelines in nephrology. You can see that most of what I feared would happen has indeed happened. </em></p><p>Practice guidelines are a recent fad in medicine. They came from non-existence 20 years ago, to over 2,000 strong today, covering all aspects of medical care. Guidelines can be educational and resemble medical textbooks in certain ways. There are key differences, however. Textbook chapters are usually single or double authored and are as authoritative as the individual authors. Different textbooks exist covering more or less the same subjects, giving a spectrum of opinion. While many authors share their personal clinical experience and make suggestions regarding treatment, they shy away from being overly specific, leaving treatment decisions to the readers. Textbook entries can be updated until literally just pre-publication. Authors are free, indeed encouraged, to scan ahead and make predictions about where the field is going, based on as yet unpublished data. Textbooks are financed by publishers who then market the product in the hope of making a profit, or at least, recoup expenses. In contrast, guidelines result from the deliberations and contributions of a &#8216;panel of experts&#8217; formed into a &#8216;work group&#8217;. Panelists frequently have financial relationships with industry with actual or apparent conflicts of interest with the outcome of deliberations. Specific treatment recommendations are made, and with great authority. Literature to be reviewed by panelists is pre-selected by staffers. The process requires a strict cutoff date &#8211; articles published after this date cannot be considered (though they may be relevant). The upshot is that guidelines are hopelessly vulnerable to being out of date when ultimately released. Guidelines are generally sponsored implicitly or explicitly by industry, via funding of specialty societies. These companies are not in the altruism business; they expect to recoup their investment through increased sales of their products, based on guideline recommendations (which are distributed for free).  It is no secret that clinical research is increasingly dominated by industry-supported studies, mostly of pharmaceutical products. It should not come as a surprise that most guidelines&#8217; bottom line is a recommendation for pharmaceutical treatment of one type or another. It should be self-evident that changes in target levels for blood pressure, cholesterol, and glycosylated hemoglobin in diabetics, will have a profound effect on sales of medications used to achieve these targets. We note in passing the inexorable decline in guideline definitions of normal blood pressure and cholesterol, and optimal HbA1C in diabetics. Have guidelines done more harm than good? It is impossible to answer this question with hard evidence. That guidelines have been accepted on faith should be troubling to scientists.</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Quintessential Medicine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p> Once guidelines are published, we cannot prevent them from being used as performance measures by payers in various pay-for-performance schemes. These are nothing more than sophisticated rationing systems, similar in design and philosophy to managed care. In this way, guidelines become the means by which payers gain control of medical decision-making. We also run the risk of being accused of not providing &#8216;standard of care&#8217; lest we ignore one or a few guidelines. This could have legal and licensing ramifications.</p><p>Guidelines promote a &#8216;one-size-fits-all&#8217; approach to care which we regard as the antithesis of good medicine. Guidelines undermine confidence in the medical profession due to actual and apparent conflicts of interest. By seeming to pronounce certain areas &#8216;settled&#8217;, guidelines inhibit research and dull inquisitive minds. Guidelines lend credence to the notion that medical care can be reduced to plugging a few numbers into an algorithm. Guidelines presume that information derived from large population studies supersedes the local knowledge of individual patients by their personal physician. We do not need guidelines. They constitute an unnecessary burden whose net effect is deleterious to patients,and to the medical profession.</p><p>Conclusions</p><p>Practice guidelines are a recent phenomenon and have proliferated without much scrutiny. Though mostly opinion-based, they have been misused and over-interpreted. Because they have not themselves been subjected to rigorous scientific analysis regarding effects on hard endpoints, it is impossible to say with certainty whether or not they have done more harm than good. Based on the analysis presented in this essay, we feel the net result of guidelines has been negative. It should be incumbent on the guideline creators and advocates to demonstrate a positive effect by constructing randomized, controlled trials. Failing this, considering the potential for abuse and harm to medical autonomy presented by guidelines, they should be abandoned.</p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Quintessential Medicine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[Dietary Disinformation]]></title><description><![CDATA[Mostly propagated by the Government]]></description><link>https://richardamerlingmd437332.substack.com/p/dietary-disinformation</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/dietary-disinformation</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Sat, 19 Jul 2025 14:59:59 GMT</pubDate><content:encoded><![CDATA[<p>The government and major medical organization have become the principal purveyors of nutritional and medical misinformation. It has become so bad that my recommendation to patients, family and friends is to do the opposite of the &#8220;official&#8221; recommendations. Here are the Big Lies:</p><p>1. Saturated fat causes heart disease and must be avoided</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Quintessential Medicine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p>2. Vegetable seed oils are heart healthy</p><p>3. Cholesterol causes heart disease and must be reduced</p><p>4. Grains (carbs) should be the major source of calories</p><p>5. Sugar is safe in moderation, even in diabetes</p><p>6. Calories in vs calories out explains obesity</p><p>7. Eat less, move more reverses obesity</p><p>8. Salt causes high blood pressure and should be avoided.</p><p></p><p>Over the past century, the country, and the world, have moved steadily away from real science and towards various forms of pseudoscience, also known as junk science. The great philosopher Karl Popper explored this in depth, using Marxism as an example of pseudoscience. They key quality of a scientific hypothesis, according to his analysis, is dis-provability. If there&#8217;s no possible experiment or observation that would be able to disprove a hypothesis, it is not truly scientific. Other examples of pseudoscience include the theory of evolution, and of course &#8220;climate change.&#8221; No observations or experiments can possibly disprove either.</p><p>As a corollary to this foundational principle, a true scientific hypothesis is never &#8220;proven;&#8221; it can only be disproven. The classic example: The hypothesis that &#8220;all swans are white&#8221; is completely disproven by the demonstration of a single black swan. Experiments can support, but not prove a hypothesis.</p><p>Take two randomized groups, one given drug &#8220;A&#8221; and the other a placebo. If the drug arm has a 1-2% reduction in the incidence of a predetermined bad outcome, does that &#8220;prove&#8221; drug &#8220;A&#8221; is effective? No, it doesn&#8217;t prove a damn thing! That notion is disproven by those in the treatment group that suffered a bad outcome. Not everyone given drug &#8220;A&#8221; derived benefit. Most didn&#8217;t. Remember this when you hear that any treatment is &#8220;proven effective!&#8221;</p><p>The gradual erosion of science in medicine was accelerated by the enthusiastic adoption of &#8220;evidence-based medicine&#8221; (EBM) beginning in the &#8216;90s. This pseudoscientific cult created an arbitrary &#8220;hierarchy&#8221; of &#8220;evidence,&#8221; promoting randomized controlled trials (RCTs) at the expense of actual clinical observations and experience, and thus paved the way for the takeover of Medicine by the Medical Industrial Complex. Unobtainable scientific proof was replaced by a legalistic definition of proof, based on statistics, or the preponderance of evidence.</p><p>EBM led to the proliferation of practice guidelines. These are issued by various professional associations but invariably funded by industry and have panels loaded with cherry-picked industry-paid doctors and scientists. Recommendations invariably promote products of the sponsors and should be viewed strictly as marketing. Guidelines have replaced critical thinking and clinical reasoning and have largely destroyed the medical profession. But the MOAG predates the EBM movement&#8212;the Dietary Guidelines for Americans (DGA).</p><p><strong>The DGA and the demonization of saturated fat</strong></p><p>The first reported case of myocardial infarction was in 1910 and the first report of coronary thrombosis was in 1912. The incidence steadily increased over the first half century to what became alarming levels during the 1950s, culminating in Dwight D. Eisenhower&#8217;s heart attack in 1955. This provoked a national debate over the cause of the epidemic of coronary artery disease. There were several plausible explanations: A huge increase in smoking, especially after WW2; major increases in sugar consumption; introduction of vegetable seed oils, margarine and shortening (Crisco). Oddly enough it was the least plausible explanation that won the debate&#8212;that saturated fat, which our ancestors thrived on for millennia, was the culprit.</p><p>This bizarre idea was pushed by a bizarre man, Ancel Keys, a self-described physiologist and originator of K-rations. He became convinced, based on observations in a handful of countries, that saturated animal fats, by increasing cholesterol, were the cause of heart disease. He pressed his case aggressively, often with personal attacks on those who disagreed with him, such as British scientist John Yudkin. His fraudulent 7-Countries Study looked at population consumption of saturated fat and incidence of coronary artery disease. He cherry-picked only the countries that fit his hypothesis (7/22, skipped France: Paradox). It was egregious junk science. He was then hired to provide nutritional guidance by the American Heart Association.</p><p>The AHA was ushered into existence and sustained by multi-million dollar grants from Procter &amp; Gamble, the original makers of Crisco; they continue to push the anti-saturated fat propaganda to this day. Thus, Keys and the AHA were shills for fake fats.</p><p>Keys, the AHA and industry lobbyists pushed through the DGA through the McGovern Commission, which led to the USDA&#8217;s Food Pyramid, stressing minimal consumption of saturated fats, 50% of calories as grains.</p><p><strong>What about sugar?</strong></p><p>Table sugar (sucrose, dextrose) is roughly 50% glucose and 50% fructose. Glucose can be utilized for energy by most cells in the body.</p><p>The glucose component of sucrose is metabolized via glycolysis with production of 2 ATP (anaerobic). Glucose stimulates insulin release which blocks fat mobilization. Pyruvate is then metabolized aerobically via the Krebs Cycle with several more ATP produced. Glycolysis consumes oxygen and produces an equal amount of CO2. Glucose provides quick energy and is rapidly depleted. Glucose not used for energy is stored as fat.</p><p>Fructose is metabolized exclusively in the liver and overconsumption leads to excess production of fatty acids which can accumulate and lead to fatty liver disease (now rampant in children!</p><p>The fructose component makes sugar particularly toxic compared with slowly digested carbohydrates, which are broken down to glucose.</p><p>The case for sugar as cause of heart disease was very strong and had considerable scientific backing. Then, in 1967, highly influential review articles were published in the New England Journal of Medicine by three Harvard scientists, Frederick Stare, Mark Hegsted, and Robert McGandy, downplaying sugar&#8217;s role in heart disease, and supporting Keys&#8217; saturated fat hypothesis. In 2016, investigative journalist Cristin Kearns unearthed letters showing these doctors were each paid $6500 ($61,000 today) for their work by the Sugar Association, who also were heavily involved in editing the articles. These payments were not made public at the time. This clever and diabolical strategy paid off, as sugar was given a pass by the public.</p><p>The food industry jumped in with scores of &#8220;low fat&#8221; processed foods, filled with seed oils and sugars.</p><p>The health of the nation began a long decline, led by the obesity epidemic, which began in 1980 and is still raging.</p><p>In the &#8216;50s-&#8216;70s, when I grew up, almost everyone was slim. No one exercised or dieted! Fat people stood out. In 1968, I was one of half a million skinny, longhaired hippies at the Woodstock Festival. Fast forward to the present day: 75% of the population is overweight/obese and most of these have the Metabolic Syndrome. The harm from these guidelines is incalculable!</p><p>If Covid is the Crime of the 21<sup>st</sup> Century, the DGA was the Crime of the 20<sup>th</sup> Century!</p><p><strong>The Metabolic Syndrome</strong></p><p>MS is defined clinically as the constellation of central obesity, type 2 diabetes, abnormal lipids (high TG, low HDL), hypertension, and vascular disease. The pathophysiology involves overconsumption of sugar and processed carbohydrates leading to chronic secretion of insulin and insulin resistance. High levels of insulin are behind most of the complications, such as hypertension. Fatty liver, caused by fructose, is also a major player in MS.</p><p>Most doctors regard diabetes and hypertension as separate diseases and treat each separately with various drugs. They simply fail to recognize they are both symptoms of an underlying metabolic syndrome that is readily reversible with a proper diet!</p><p>Insulin signals cells to store energy as fat, and to grow. Hyperinsulinemia is the obvious link between obesity and over 70% of cancers.</p><p>Metabolic syndrome is very likely responsible for the epidemic of Alzheimer&#8217;s dementia.</p><p>The key to reversing obesity and the MS is to lower insulin levels. This is accomplished by cutting out most sugars, reducing carb intake to &lt;100 g/d, eliminating seed oils, and intermittent fasting (no snacks). Must read labels and avoid the center aisles of the supermarkets! If people stop buying this toxic garbage, Big Food will stop making it.</p><p><strong>Fat Fysiology:</strong></p><p>Fat is oxidized in the mitochondria with production of 129 ATP for a long chain fatty acid. For each mole of oxygen consumed, only 0.7 mole of CO2 is generated. If you believe CO2 is destroying the planet, you should go keto. Fat oxidation provides virtually limitless energy and produces ketones, which are the preferred energy substrate for the brain and heart.</p><p>Nutritional ketosis is the default condition for which we were designed.</p><p>Oxidation of saturated fat produces intermediaries that block the action of insulin to store energy in adipose tissue. Polyunsaturated fat oxidation lacks this benefit.</p><p>Vegetable seed oils contain mostly PUFA which are pro-inflammatory and obesogenic. When heated they become aldehydes that are quite toxic.</p><p>The guideline-driven switch from saturated fat to polyunsaturated seed oils is one of the principal drivers of the obesity/metabolic syndrome epidemic.</p><p><strong>Cholesterol</strong></p><p>The Cholesterol scam has also harmed millions, while generating billions in Pharma profits.</p><p>1. Cholesterol doesn&#8217;t cause heart disease. This hypothesis has been soundly disproven by the millions with heart disease and low or &#8220;normal cholesterol&#8221; and the millions with high cholesterol and no heart disease. </p><p>2. Cholesterol is a vital substance synthesized by most cells in the body. It&#8217;s essential to brain and nerve function and plays a key role in the immune system.</p><p>3. Cholesterol is the necessary backbone for synthesis of vitamin D, cortisol, aldosterone and the sex hormones.</p><p>4. Blocking the mevalonate pathway (statins) depletes other key compounds such as dolichols and CoEnzyme Q10; vital for energy transport. It&#8217;s inconceivable that blocking this key biosynthetic pathway could be anything but harmful</p><p>5. The cholesterol blocked by statins is the same molecule in HDL (good) and LDL (bad).</p><p>6. Dietary cholesterol has no impact on blood levels</p><p>7. Studies of cholesterol lowering show no mortality benefit.</p><p>8. Phony &#8220;relative risk reduction&#8221; math is used to sell statins which at most produce 1-3% absolute risk reduction in &#8220;events.&#8221;</p><p>9. As in most Pharma studies, harms are downplayed but are very real and sometimes deadly. Examples: myositis, rhabdomyolysis, brain fog (aka dementia!), diabetes, neuropathies, ALS</p><p><strong>Caloric Nonsense:</strong></p><p>This fiction creates the impression that calories from different foods are equivalent in terms of weight control and that fat (9 kcal/gm) is more obesogenic than carbs or protein (4 kcal/gm). This is demonstrably absurd. The insulin response to food is what counts: Carbs/sugars trigger insulin release which drives energy storage as fat. Fat doesn&#8217;t provoke insulin or energy storage. Constant snacking or multiple small meals as many recommend will guarantee continuous weight gain. To utilize energy stored as fat, insulin levels must be suppressed. This requires a prolonged fast (12-18 hours) and low carbohydrate intake.</p><p>Carbs are an inefficient source of energy and produce insulin/blood glucose peaks and valleys which drive more carb/sugar intake.</p><p>Weight reduction strategies based on calorie reduction never work!</p><p>Salt:</p><p>Salt is essential for life and should be restricted only in those with heart, kidney, or liver failure. Everyone else should liberally use salt to taste. Low salt intake produces a variety of health problems and triggers counter regulatory hormonal systems that create harm.</p><p><strong>In Summary:</strong></p><p>To become healthy, do the opposite of official &#8220;guidance.&#8221;</p><p>1. Eat saturated fats: Butter, cream, meat, eggs, bacon..</p><p>2. Avoid Vegetable seed oils like the plague</p><p>3. Cholesterol lowering is harmful. Don&#8217;t take statins.</p><p>4. Grains (carbs) should be consumed sparingly</p><p>5. Sugar is to be avoided.</p><p>6. Don&#8217;t count calories</p><p>7. Muscle strengthening with resistance is highly beneficial</p><p>8. Salt your food!</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Quintessential Medicine is a reader-supported publication. To receive new posts and support my work, consider becoming a free or paid subscriber.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[The Tyranny of Evidence-Based Medicine]]></title><description><![CDATA[from the Journal of American Physicians and Surgeons]]></description><link>https://richardamerlingmd437332.substack.com/p/the-tyranny-of-evidence-based-medicine-944</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/the-tyranny-of-evidence-based-medicine-944</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Mon, 07 Apr 2025 18:00:34 GMT</pubDate><content:encoded><![CDATA[<p>https://jpands.org/vol26no4/amerling.pdf</p><p>More on EBM:  xhttps://rumble.com/v4ku6sn-dr.-richard-amerling-evidence-based-medicine-ruined-medicine-aflds-freedom-.html</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading! Subscribe for free to receive new posts and support my work.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[The Nazification of American Medicine]]></title><description><![CDATA[This is an essay I published on the AAPS website in 2022.]]></description><link>https://richardamerlingmd437332.substack.com/p/the-nazification-of-american-medicine</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/the-nazification-of-american-medicine</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Fri, 21 Mar 2025 18:00:29 GMT</pubDate><content:encoded><![CDATA[<p>This is an essay I published on the AAPS website in 2022.  Sadly, it is still all too relevant.</p><p></p><p>https://aapsonline.org/the-nazification-of-american-medicine/</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading! Subscribe for free to receive new posts and support my work.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[Let's not panic over measles!]]></title><description><![CDATA[Statement from Dr. Jane Orient on aapsonline.org]]></description><link>https://richardamerlingmd437332.substack.com/p/lets-not-panic-over-measles</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/lets-not-panic-over-measles</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Tue, 04 Mar 2025 12:49:54 GMT</pubDate><content:encoded><![CDATA[<p>Please feel free to share:</p><p></p><p>https://aapsonline.org/public-health-watch-measles-alert/</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading! Subscribe for free to receive new posts and support my work.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[Whither quality?]]></title><description><![CDATA[Zen and the Art of Health Maintenance]]></description><link>https://richardamerlingmd437332.substack.com/p/whither-quality</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/whither-quality</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Wed, 19 Feb 2025 17:10:46 GMT</pubDate><content:encoded><![CDATA[<p>&#8220;Quality Assurance&#8221; became a buzzword in medicine around the turn of the last century and with it, various metrics. These were derived from guidelines which were themselves derived from &#8220;evidence-based medicine.&#8221; This is an essay I published in 2004 regarding the definition of quality in medicine.</p><p></p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading! Subscribe for free to receive new posts and support my work.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p></p><h1><strong>Zen and the art of health maintenance</strong></h1><p>Richard Amerling, MD</p><p>March 2004</p><p>&#8220;Peace of mind isn&#8217;t at all superficial, really; it&#8217;s the whole thing. That which produces it is good maintenance; that which disturbs it is poor maintenance.&#8221;</p><p>Robert Pirsig; Zen and the Art of Motorcycle Maintenance; 1974</p><p>While listening to a colleague lecture about quality assurance in the dialysis unit, it occurred to me that perhaps he didn't have any idea what he was talking about. I suddenly realized what was missing from the debate over the quality of medical care--a viable definition of quality. Traces of Robert Pirsig's seminal novel, "Zen and the Art of Motorcycle Maintenance," which I read in 1974, came rushing back. In it, the protagonist (author) literally went insane in pursuit of this. He asks his philosophy students to define quality, and they come up short. He tells them,</p><p>&#8220;I think there is such a thing as Quality, but that as soon as you try to define it, something goes haywire. You can&#8217;t do it.&#8221;</p><p>After a few days he comes up with,</p><p>&#8220;Quality is a characteristic of thought and statement that is recognized by a non-thinking process. Because definitions are a product of rigid, formal thinking, quality cannot be defined.&#8221;</p><p>Of course, he is not satisfied by this non-definition, and pushes further to an epiphany:</p><p>&#8221;Quality couldn&#8217;t be independently related with either the subject or the object but could be found only in the relationship of the two with each other. It is the point at which subject and object meet. Quality is not a thing. It is an event. It is the event at which the subject becomes aware of the object.&#8221;</p><p>More later.</p><p>The major problem with current concepts of quality in health care is that they are tied to outcomes. Outcomes are measured, to the extent they can be, and then practices or procedures associated with good outcomes are retrospectively labeled as high quality. Several large flaws are inherent in this methodology.</p><p>First is the retrospective nature of the process. Retrospective studies, which the medical literature is full of, are difficult to interpret at best. This is because many other variables may have influenced the outcome, but were not controlled for. The only way to safely conclude that a given treatment made a difference is by performing a double blind, placebo-controlled study. These prospective studies form the core of scientific medicine and distinguish it from so called alternative medicine. If more patients in the treatment group respond favorably, and the difference in response rates between the two groups rises to statistical significance, we can conclude that the treatment is effective. If the difference is only slight, however, we cannot come to that conclusion. What is always fascinating about these studies is that the placebo works, sometimes in a large number of patients. Likewise, the placebo group often reports similar side effects as the active group. Very often interventions that seemed effective when viewed retrospectively have proven to be ineffective when tested prospectively.</p><p>Another large flaw in the &#8216;good outcome=quality&#8217; process is that populations can differ widely. A group might have a good (or bad) outcome that is completely unrelated to any treatment effect, but rather is due to the inherent health of the population. This is one reason why the so-called &#8216;health maintenance organizations&#8217; may have decent &#8216;quality&#8217; reports: their patient population has been pre-selected to be relatively healthy. In such a group it matters little what sort of care is provided, as they will tend to do well regardless. Traditional quality=outcome measures will tell little about the actual process of health care within these organizations. Harvard Medical School may well be able to boast of the success of their graduates. Does this mean the quality of the education at Harvard is superb, or that the entering class is handpicked from the cream of the cream of undergraduate applicants, who would succeed in any setting?</p><p>The third major problem with this approach is that it is based on the study of large populations, whereas physicians deal with individual patients, one at a time. Even well designed, double blind, prospective studies (which form the basis of what is called &#8216;evidence-based medicine,&#8217; or EBM) can be difficult to apply to the individual. All they do is give a statistical likelihood that a given patient will respond favorably to the treatment studied. Physicians must exercise judgment in choosing whom to treat and with what, and then follow assiduously to monitor the effects of treatment (office EBM). The outcome=quality approach produces &#8216;guidelines&#8217; which, if followed, ought to lead to good outcomes, i.e., good &#8216;quality.&#8217; However, the &#8216;guideline&#8217; thesis has never been tested. Do patients treated according to guidelines do better than those treated as individuals by their own physicians? Guidelines are completely useless when dealing with a new problem. They are too-often misused as mandates, with real life consequences for medical malpractice and reimbursement policy.</p><p>Back to Pirsig.</p><p>Earlier in the book he talks of an instruction manual for a bicycle that states,</p><p>&#8220;Assembly of Japanese bicycle requires great peace of mind.&#8221;</p><p>Then he explains,</p><p>&#8220;Technology presumes there&#8217;s just one right way to do things and there never is&#8230;the art of the work is just as dependent upon your own mind and spirit as it is upon the material of the machine. That&#8217;s why you need the peace of mind.&#8221;</p><p>He then uses the craftsman analogy to shoot an arrow through the heart of the guidelines movement, 20+ years in advance:</p><p>&#8220;Sometime look at a novice workman or a bad workman and compare his expression with that of a craftsman whose work you know is excellent and you&#8217;ll see the difference. The craftsman isn&#8217;t ever following a single line of instruction. He&#8217;s making decisions as he goes along. For that reason he&#8217;ll be absorbed and attentive to what he&#8217;s doing even though he doesn&#8217;t deliberately contrive this. His motions and the machine are in a kind of harmony. He isn&#8217;t following any set of written instructions because the nature of the material at hand determines his thoughts and motions, which simultaneously change the nature of the material at hand. The material and his thoughts are changing together in a progression of changes until his mind&#8217;s at rest at the same time the material&#8217;s right.&#8221;</p><p>The quality is in the interaction between craftsman and his work. A good interaction produces an excellent result. This could just as easily be describing a doctor performing an evaluation of a patient. Quality is directly linked to caring:</p><p>&#8220;&#8230;care and Quality are internal and external aspects of the same thing. A person who sees Quality and feels it as he works is a person who cares. A person who cares about what he sees and does is a person who&#8217;s bound to have some characteristics of Quality.&#8221;</p><p>Now we get to the Zen of health maintenance. Quality in healthcare occurs at the cutting edge between subject and object, the doctor-patient interaction. Anything that enhances this relationship improves Quality; anything that interferes with it destroys Quality. If the interaction between patient and physician is positive, craftsmanlike, serene, and secure, this will afford the physician the best possible chance of figuring out exactly what is wrong with the patient. The patient will feel the caring, and that, in fact, begins the healing process.</p><p>When seen in this light, the factor that has most interfered with the doctor-patient interaction is the interposition of third party payers between doctor and patient. The most egregious example is the so-called &#8216;health maintenance organization.&#8217; Most pay physicians a modest monthly sum to assume primary care duties for patients. This creates a strong financial incentive to avoid seeing any of these patients. Any visits are likely to be short, stressful affairs with much negative emotion on both sides. These organizations also specialize in erecting barriers to secondary and tertiary care.</p><p>They also, along with Medicare and Medicaid, have effectively removed money from this basic relationship, which also helps destroy Quality. In Medicine, money is essential to Quality. Money buys a pleasant office, helpful staff, the latest equipment, books, computers, education, and, most important, time. Time spent with a patient, or thinking about a patient, is the <em>sine qua non</em> of a good patient-physician interaction. Current levels of physician reimbursement have made it all but impossible to spend adequate time with patients.</p><p>Quality in healthcare has been destroyed by various third parties stripping money away from physicians and other providers of care, such as nurses and hospitals. Parallel with the wholesale destruction of Quality we have witnessed the rise of various &#8220;quality initiatives,&#8221; &#8220;quality indicators,&#8221; &#8220;quality assurance committees,&#8221; &#8220;treatment guidelines,&#8221; and the like, all of which completely miss the point, and in fact make things worse by diverting even more time and money away from actual caring. The decline in quality has been accompanied by a decrease in the ratio of caregivers to total health care workers. The ballooning administrative sector is choking off the clinical sector.</p><p>The ideal setting in which to experience the art of health maintenance is the private physician&#8217;s office, where care is rendered for a fee, to be paid directly by the patient to the physician. This fee solidifies the relationship between doctor and patient. It commits the physician to do his utmost to promote the patient&#8217;s well being, and it places the patient firmly in control. It guarantees that the physician works for the patient and is responsible to him, rather than a third party. It assures complete confidentiality. Of course, nothing prevents patients from purchasing insurance to protect them from catastrophic illness or injury. But this should always remain external to the doctor-patient relationship, lest it interfere with Quality.</p><p>In the hospital setting Quality means more and better nurses, who are liberated from mind-numbing paperwork, so they can spend more time with their patients.</p><p>Across the country, increasing numbers of physicians are severing their ties to third party payers, opting to recreate the sort of high quality private practice that made American Medicine the envy of the world. Let the trend continue. And let us make Robert Pirsig&#8217;s fabulous book required reading for everyone involved in health care.</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading! Subscribe for free to receive new posts and support my work.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[Living systems are irreducibly complex]]></title><description><![CDATA[DNA, RNA, amino acids, and multiple enzymes must be present and functional]]></description><link>https://richardamerlingmd437332.substack.com/p/living-systems-are-irreducibly-complex</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/living-systems-are-irreducibly-complex</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Wed, 05 Feb 2025 19:35:43 GMT</pubDate><content:encoded><![CDATA[<p>Take a look under the hood of cellular replication; you will understand the impossibility of random generation of living cells.</p><p></p><p>https://evolutionnews.org/2025/01/circular-reasoning-in-origin-of-life-research-insights-from-a-recent-study-on-the-genetic-code/</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading! Subscribe for free to receive new posts and support my work.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[The Dietary Guidelines are a Disaster]]></title><description><![CDATA[All guidelines are inherently anti-scientific]]></description><link>https://richardamerlingmd437332.substack.com/p/the-dietary-guidelines-are-a-disaster</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/the-dietary-guidelines-are-a-disaster</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Wed, 05 Feb 2025 19:30:36 GMT</pubDate><content:encoded><![CDATA[<p></p><p>All guidelines are, at best, consensus statements and thus antiscientific. They are heavily influenced by financial interests, directly or indirectly.<br>They have been given enormous power to control menus across federally-funded entities.<br>By pushing Americans away from traditional animal sources of fats and protein (meat, eggs, full fat dairy) into processed &#8220;foods&#8221; with fake fats and loads of sugar, the dietary guidelines from 1977 led to the epidemic of obesity and metabolic diseases we are witnessing.<br>The idea that the federal government should be telling Americans what to eat is beyond absurd.<br>The dietary guidelines should be eliminated by the incoming Secretary of HHS. Failing that, they should at least be stripped of any power to influence food choices.</p><p></p><p>https://www.theepochtimes.com/health/meat-dairy-and-ultra-processed-foods-create-riffs-for-us-dietary-guidelines-5794739?utm_source=ref_share&amp;utm_campaign=copy</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading! Subscribe for free to receive new posts and support my work.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[Restoring Science to Medicine ]]></title><description><![CDATA[We must reject pseudoscience.]]></description><link>https://richardamerlingmd437332.substack.com/p/restoring-science-to-medicine</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/restoring-science-to-medicine</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Sat, 11 Jan 2025 16:45:08 GMT</pubDate><enclosure url="https://substack-post-media.s3.amazonaws.com/public/images/70f715e2-48b1-4254-b344-eab92b89a771_4991x3743.jpeg" length="0" type="image/jpeg"/><content:encoded><![CDATA[<p>I came to Medicine with a strong science background. After graduating Stuyvesant High School, a science-oriented special school in NYC, I was a Physics major for a year at SUNY Stony Brook. I then transferred to CCNY and eventually went pre-med, taking advanced courses in chemistry, biology and biochemistry. My medical education at the Catholic University of Louvain heavily emphasized the Basic Sciences, and since we had no computers or smartphones, memorization was essential. I arrived back in the US to do clinical training and was head and shoulders above my US-schooled counterparts in this regard. After finishing my IM residency in NY, I served a year as Chief Medical Resident, where one of my major responsibilities was organizing the weekly Medical Grand Rounds.</p><p>I was able to land a Nephrology Fellowship at Univ of Penn, which was (and probably still is) one of the top programs in the country. Nephrology is a specialty closely linked to Chemistry. I am a scientist who then became a physician.</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading! Subscribe for free to receive new posts and support my work.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div><p>Over the past century, the country, and the world, have moved steadily away from real science and towards various forms of pseudoscience, also known as junk science. The great philosopher Karl Popper explored this in depth, using Marxism as an example of pseudoscience. They key quality of a scientific hypothesis, according to his analysis, is dis-provability. If there&#8217;s no possible experiment or observation that would be able to disprove a hypothesis, it is not truly scientific.</p><p>As a corollary to this foundational principle, a true scientific hypothesis is never &#8220;proven;&#8221; <em>it can only be disproven</em>. The classic example: The hypothesis that &#8220;all swans are white&#8221; is completely disproven by the demonstration of a single black swan. Experiments can support, but not prove a hypothesis.</p><p>Other examples of pseudoscience include the theory of evolution, and of course &#8220;climate change.&#8221; No observations or experiments can possibly disprove either. Let us delve into these two, just a bit. I&#8217;m not asking you to believe me, but it&#8217;s important in science to have an open mind and to question dogma.</p><p>Like most of you, I was thoroughly indoctrinated from grade school, and on, that evolution was firmly established as bedrock science. As I worked through the medical school science curriculum, it became clear this was far from true. Evolution was something that may have occurred in the past and there was no experiment that could ever disprove it. The theory was not truly scientific in the Popperian system. I came to understand that living biological systems were &#8220;irreducibly complex&#8221; at a cellular and subcellular level, and that even with unlimited time, could never spontaneously come together. Think about the multiple enzymes, intermediaries, NAD to NADH, ADP to ATP, involved in the Krebs Cycle? Every enzyme, produced by ribosomes with instruction from DNA to mRNA, must be present and perfect. How could that possibly have arisen by random forces? None of this was known in Darwin&#8217;s time, and to his credit, he never attempted to explain the origin of life.</p><p>Having rejected the spontaneous generation of life, the notion of random mutations generating stepwise increases in the complexity of organisms also became untenable. &#8220;Natural Selection&#8221; could filter out defective mutations but couldn&#8217;t account for the creation of new forms. New additions, such as eyes, arms, wings, would need to be fully functional from day 1 to be of any &#8220;survival benefit.&#8221;</p><p>I came to believe in &#8220;intelligent design&#8221; long before it became a thing. Ultimately, this led to a belief in a Divine Creator, possessing an intelligence so profound as to be unfathomable.</p><p>The general acceptance of the Theory of Evolution has had an extremely negative impact on science, medicine, and the course of history. It provided a mechanistic (atheistic) explanation for the miracle of life, and demoted Man as &#8220;hairy ape&#8221; which was literally dehumanizing and did away with morality. The Darwinian imperatives became survival, reproduction, and hedonism.</p><p>It provided a (pseudo)scientific basis for Naziism and Communism, and of course for Eugenics and Transhumanism! In Medicine it opened the door to the &#8220;perfectibility of man&#8221; via pharmaceuticals and vaccines as opposed to man being created perfectly and subsequently &#8220;devolving.&#8221;</p><p>&#8220;Climate Change&#8221; is pure pseudoscience. It began in the &#8216;70s with &#8220;global cooling&#8221; and fears of a &#8220;new Ice Age.&#8221; When temperatures didn&#8217;t drop, the alarmists jumped to &#8220;man-made global warming&#8221; which was ostensibly caused by increased CO2 emissions. When this failed to pan out, &#8220;climate change&#8221; was born. This allowed any possible observation of temperature, polar ice, or weather events to be attributed to this bogus theory. In other words, it is not susceptible to ever being disproven, and thus qualifies as classic pseudoscience. The &#8220;de-growth&#8221; far Left ideology behind this movement places it in the realm of political science. The idea that small changes in the amount of atmospheric CO2, a trace gas only marginally produced by human activity, can affect global temperatures is implausible to the point of absurdity. The dominant player in climate is clearly the sun, which anyone can demonstrate simply by walking from the sun into the shade! Global warming, or now &#8220;climate change,&#8221; exists only in various computer models, none of which has ever correctly predicted a damn thing. These fools can barely predict the weather more than a day or two in advance!</p><p>Questioning either of these dogmas immediately gets you labeled as a &#8220;science denier.&#8221; No! I am a proud pseudoscience denier.</p><p>The erosion of science in medicine was accelerated by the enthusiastic adoption of &#8220;evidence-based medicine&#8221; (EBM) beginning in the &#8216;90s. This pseudoscientific cult created an arbitrary &#8220;hierarchy&#8221; of &#8220;evidence,&#8221; promoting randomized controlled trials (RCTs) at the expense of actual clinical observations and experience.</p><p>This Canadian construct arrogantly claimed the moral and scientific high ground by implying that everything before EBM was based on superstition, sorcery, alchemy, and witchcraft.</p><p>Problems with EBM are many. &#8220;Evidence&#8221; is not science and can be found or produced to support any conceivable hypothesis (see above).</p><p>The arbitrary exaltation of RCTs allowed industry to dominate the medical literature with their funded, biased, ghost-written, gift-authored, &#8220;studies&#8221; that are rarely more than well-disguised marketing.</p><p>In the same way that Pharma ads on television allow them to control content, Pharma ads and reprint purchases give them control over the medical journals, editors, and peer reviewers. The medical &#8220;evidence base&#8221; is corrupt.</p><p>The promotion by EBM of RCTs over clinical experience is absurd on its face&#8212;RCTs are easily manipulated and often flawed, while the clinical experience of physicians is the actual basis of Medicine. Even a well-designed, unbiased RCT (try to find one) provides at best a statistical probability that any treatment will be helpful to the patient in your office. There is never enough granular information in a trial to allow doctors to apply the results broadly to everyone, yet that is exactly what has developed.</p><p>Take, for example, a typical drug trial with two randomized groups, one given drug &#8220;A&#8221; and the other a placebo. If the drug arm has a 1-2% reduction in the incidence of a predetermined bad outcome, does that &#8220;prove&#8221; drug &#8220;A&#8221; is effective? No, it doesn&#8217;t prove a damn thing! That notion is disproven by those in the treatment group that suffered a bad outcome. Not everyone given drug &#8220;A&#8221; derived benefit. Most didn&#8217;t. Not everyone in the placebo arm did badly. Most did well. Remember this when you hear that any treatment is &#8220;proven effective!&#8221; Scientific theories can only be disproven. Unobtainable scientific proof was replaced by a legalistic definition of proof, based on statistics, or the preponderance of evidence.</p><p>Using principles derived from EBM, Big Pharma funded expert panels to create &#8220;clinical practice guidelines&#8221; for the treatment of now virtually every condition. Not coincidentally, many panelists have significant financial conflicts of interest&#8212;they are paid by industry. Unsurprisingly, most CPGs recommend Pharma treatments, larger and larger doses, and to ever bigger swaths of the population.  Outcomes are poor with this approach. Patients are being harmed and life expectancy is going in the wrong direction.</p><p>Guidelines typically focus on &#8220;risk factors&#8221; for disease, rather than the actual disease. These are most often numerical &#8220;targets,&#8221; such as blood pressure, LDL-C, T-scores, or glycosylated hemoglobin. These targets move: Ever-increasing drug treatments are justified to get patients &#8220;to goal.&#8221; &#8220;Normal&#8221; blood pressure was lowered from 140/90 to 120/80, even in the elderly, based on a flawed study published in 2015. This has led to an increase in serious complications.</p><p>Treating type 2 diabetes with drugs that simply lower blood glucose, rather than reversing disease with a proper diet, is malpractice in my view. But this is what most doctors routinely do. Prescribing insulin to patients with type 2 diabetes whose insulin levels are already too high creates weight gains and makes their underlying metabolic syndrome worse.</p><p>Giving statins to everyone with LDL cholesterol slightly above what is now proclaimed as &#8220;normal&#8221; has caused enormous harm, including the current epidemic of heart failure, severe forms of neuropathy, myopathy, and dementia (which they call &#8220;brain fog&#8221;). Cholesterol is a vital substance synthesized by most cells in the body. Interfering with this pathway makes no sense scientifically and should never have been done.</p><p>Disease reversal by addressing underlying causes is almost never addressed. This is what most medical practices have devolved to&#8212;treating numbers, rather than patients! Guidelines have replaced critical thinking and clinical reasoning; they have taken over medical education and are destroying the medical profession.</p><p>Guidelines have allowed the &#8220;standard of care&#8221; to morph into &#8220;standardized care.&#8221; This is nothing more than &#8220;one-size-fits all,&#8221; which is the antithesis of good, individualized care. Going outside the &#8220;standard&#8221; places physicians in jeopardy of losing their employment, certification, or even their license to practice. This is the complete triumph of &#8220;Public Health,&#8221; a Marxist creation, over individualized care.</p><p>EBM paved the way for the takeover of Medicine by the Medical Industrial Complex. By arbitrarily redefining science and elevating &#8220;expert&#8221; committees, the pseudoscientific EBM has led the way to totalitarianism.</p><p>Granting unjustified authority to various official bodies, such as the CDC or WHO, most of whose members do not even treat patients, has led us to the medical tyranny we have been experiencing over the last few years. What is &#8220;misinformation and disinformation?&#8221; Anything that runs counter to the official &#8220;guidance.&#8221;</p><p>Restoring science to medicine requires that we first jettison pseudoscience. The term &#8220;evidence-based&#8217; should be stricken from the medical lexicon. It is meaningless and should go away, along with &#8220;essentially&#8221; and &#8220;basically.&#8221;</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading! Subscribe for free to receive new posts and support my work.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[The Tyranny of Evidence-Based Medicine]]></title><description><![CDATA[EBM was created with good intentions, perhaps but...]]></description><link>https://richardamerlingmd437332.substack.com/p/the-tyranny-of-evidence-based-medicine</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/the-tyranny-of-evidence-based-medicine</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Mon, 19 Aug 2024 12:49:32 GMT</pubDate><content:encoded><![CDATA[<p>https://aapsonline.org/covid-19-response-and-the-tyranny-of-evidence-based-medicine/</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading! Subscribe for free to receive new posts and support my work.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item><item><title><![CDATA[What's wrong with Evidence-Based Medicine?]]></title><description><![CDATA[Pretty much everything.]]></description><link>https://richardamerlingmd437332.substack.com/p/whats-wrong-with-evidence-based-medicine</link><guid isPermaLink="false">https://richardamerlingmd437332.substack.com/p/whats-wrong-with-evidence-based-medicine</guid><dc:creator><![CDATA[Richard Amerling, MD]]></dc:creator><pubDate>Fri, 16 Aug 2024 16:01:22 GMT</pubDate><content:encoded><![CDATA[<p>https://rumble.com/v4ku6sn-dr.-richard-amerling-evidence-based-medicine-ruined-medicine-aflds-freedom-.html</p><div class="subscription-widget-wrap-editor" data-attrs="{&quot;url&quot;:&quot;https://richardamerlingmd437332.substack.com/subscribe?&quot;,&quot;text&quot;:&quot;Subscribe&quot;,&quot;language&quot;:&quot;en&quot;}" data-component-name="SubscribeWidgetToDOM"><div class="subscription-widget show-subscribe"><div class="preamble"><p class="cta-caption">Thanks for reading! Subscribe for free to receive new posts and support my work.</p></div><form class="subscription-widget-subscribe"><input type="email" class="email-input" name="email" placeholder="Type your email&#8230;" tabindex="-1"><input type="submit" class="button primary" value="Subscribe"><div class="fake-input-wrapper"><div class="fake-input"></div><div class="fake-button"></div></div></form></div></div>]]></content:encoded></item></channel></rss>